Senior Research Associate/Principal Research Associate, Medicinal Chemistry

Ribon Therapeutics is seeking a highly-motivated, experienced organic chemist to help build our internal medicinal chemistry team. This is primarily a lab-based role and applicants must have experience in small molecule multistep synthesis, purification, and analytical techniques. We are seeking applicants with strong problem-solving skills who are excited about tackling complex synthetic and medicinal chemistry challenges. The ideal candidate will also have strong communication skills, work effectively in a dynamic, matrix team environment, and demonstrate creativity, flexibility, initiative, and self-motivation.

Responsibilities

• Synthesize, purify and characterize small molecule compounds as singletons and in parallel.
• Have an up-to-date understanding of the chemical literature, including an awareness of current synthetic techniques.
• Interact with structural biologists, computational chemists, biologists, biochemists, and pharmacologists as part of a multidisciplinary team.
• Interpret biological data and incorporate into compound design.
• Present results to chemistry, project teams, and broader audiences.
• Keep detailed laboratory notebooks and contribute to patent application and publication preparation.
• Manage chemistry CROs.
• Apply good laboratory practices with an emphasis on safety.

Qualifications

• 3+ years of experience in the pharmaceutical/biotech industry with a Bachelor’s or Master’s degree in chemistry.
• Experience in multistep synthesis working on milligram to 100+ gram scale.
• Experience with purification techniques including silica gel chromatography and mass-directed HPLC purification.
• Understand reaction sequence troubleshooting and route improvement.
• Familiar with chemistry search engines (SciFinder or Reaxys).
• Meticulous, self-motivated, and independent.

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If you are interested in joining Ribon’s team, please email your resume to [email protected].