Senior Research Associate/Principal Research Associate, Medicinal Chemistry

Ribon Therapeutics is seeking a highly-motivated, experienced organic chemist to help build our internal medicinal chemistry team. This is primarily a lab-based role and applicants must have experience in small molecule multistep synthesis, purification, and analytical techniques. We are seeking applicants with strong problem-solving skills who are excited about tackling complex synthetic and medicinal chemistry challenges. The ideal candidate will also have strong communication skills, work effectively in a dynamic, matrix team environment, and demonstrate creativity, flexibility, initiative, and self-motivation.


  • Synthesize, purify and characterize small molecule compounds as singletons and in parallel.
  • Have an up-to-date understanding of the chemical literature, including an awareness of current synthetic techniques.
  • Interact with structural biologists, computational chemists, biologists, biochemists, and pharmacologists as part of a multidisciplinary team.
  • Interpret biological data and incorporate into compound design.
  • Present results to chemistry, project teams, and broader audiences.
  • Keep detailed laboratory notebooks and contribute to patent application and publication preparation.
  • Manage chemistry CROs.
  • Apply good laboratory practices with an emphasis on safety.


  • 3+ years of experience in the pharmaceutical/biotech industry with a Bachelor’s or Master’s degree in chemistry.
  • Experience in multistep synthesis working on milligram to 100+ gram scale.
  • Experience with purification techniques including silica gel chromatography and mass-directed HPLC purification.
  • Understand reaction sequence troubleshooting and route improvement.
  • Familiar with chemistry search engines (SciFinder or Reaxys).
  • Meticulous, self-motivated, and independent.

If you are interested in joining Ribon’s team, please email your resume to [email protected].

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