Research Associate/Senior Research Associate, in vivo Pharmacology

Ribon is a clinical stage biopharmaceutical company pursuing the development of novel small molecules targeting stress support pathways in cancer and inflammation using our proprietary BEACON+ (Blocking the Enzyme Activity Component of NAD+) platform.  We explore novel areas of disease biology and use our expertise in drug discovery to develop new and effective treatments for patients with high unmet need.

We are seeking an in vivo biologist to join our culture of transparency, scientific rigor, and fun!  The successful candidate will serve as an integral member of a multidisciplinary drug discovery project team developing novel small molecule inhibitors targeting novel enzyme families, with our initial efforts focused on monoPARPs.  The candidate will report to the head of in vivo pharmacology and employ a variety of molecular and cell biology techniques to understand target biology and manage in vivo studies for small molecule inhibitors in oncology and inflammation models.  Experience in neuroscience is a plus but not required.

Key Responsibilities 

  • Routine analysis of in vivo data of ongoing programs
  • Develop protocols and perform pharmacodynamic and efficacy studies with small molecule inhibitors
  • Work with CROs to conduct in vivo studies for target validation programs

Education and Requirements

  • BS/MS in biology or a related field
  • A minimum of 3-5 years of relevant laboratory experience
  • Experience in in vivo studies in oncology and inflammation is highly desirable, experience in neuroscience animal models is an advantage
  • Experience in a range of molecular and cell biological techniques is highly desirable, including:
    • Western blot analysis
    • ELISA
    • qPCR
  • Experience in mammalian tissue culture techniques is a plus
  • Backgrounds in oncology, inflammation, and/or neuroscience are a distinct advantage
  • Excellent analytical, organizational and communication skills are essential
  • The successful candidate can work independently yet thrives in a team environment
  • Work well with high-paced, but fun working environment

If you are interested in joining Ribon’s team, please email your resume to [email protected]

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