Director, DMPK

Ribon Therapeutics is a biotechnology company pioneering the discovery of new cancer medicines that target monoPARP proteins, critical regulators of cancer survival mechanisms. Ribon offers a fast-paced, team-oriented work environment and a comprehensive benefits package, including health, dental, 401(k), paid vacation, and much more.  Ribon is located in Lexington, Massachusetts.

Job Summary

The candidate will be an integral member of a team responsible for discovering and developing transformative cancer medicines that target cellular stress pathways.  This position reports to the Vice-President of Molecular Discovery and the individual will be responsible for:

  • Leadership in preclinical and early clinical studies, including but not limited to in vitro and in vivo ADME assays, PK/TK support, M&S;
  • Representing DMPK function in cross functional project team and provide critical feedbacks to project teams from DMPK point of view;
  • Leading regulatory related activities in DMPK areas for R&D and generating and reviewing documents such as investigator’s brochures, INDs & CTAs, and providing scientific support on all licensing activities;
  • Managing collaborations with CRO/CMO for outsourcing activities.
  • Ensuring reporting timelines for all DMPK related reports. Expected to review, edit, and offer critical feedbacks to the reports generated by CROs.

Job Requirements

  • Ph.D. degree in relevant discipline with 10+ years of industrial experience, ideally within both large pharma and biotech, with 3+ years of experience as project leader or project representative
  • Experience managing DMPK CROs
  • Experience with preparation of regulatory documents, such as IND, CTA, NDA, etc.
  • Broad background knowledge in DMPK with strong expertise in at least one DMPK area, preferably drug metabolism or modeling & simulation
  • Working knowledge of DMPK related regulations and regulatory guidelines from ICH, FDA and EMA
  • Track record of contribution to project teams enabling achievement of milestones in a time efficient manner
  • Excellent communication, presentation skills, and attention to detail

If you are interested in joining Ribon’s team, please email your resume to [email protected].

Join our team of experts.
Find Out More